Optimizing 2D gas chromatography mass spectrometry for robust tissue, serum and urine metabolite profiling
نویسندگان
چکیده
منابع مشابه
Optimizing 2D gas chromatography mass spectrometry for robust tissue, serum and urine metabolite profiling
Two-dimensional gas chromatography mass spectrometry (GCxGC-MS) is utilized to an increasing extent in biomedical metabolomics. Here, we established and adapted metabolite extraction and derivatization protocols for cell/tissue biopsy, serum and urine samples according to their individual properties. GCxGC-MS analysis revealed detection of ~600 molecular features from which 165 were characteriz...
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ژورنال
عنوان ژورنال: Talanta
سال: 2017
ISSN: 0039-9140
DOI: 10.1016/j.talanta.2017.01.003